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分子植物卓越中心揭示维持DNA甲基化和基因组稳定的新机制

2021-08-31 分子植物科学卓越创新中心
【字体:

yuyinbobao

  8月28日,PNAS在线发表了九州体育分子植物科学卓越创新中心研究员朱健康研究组完成的题为Pathway conversion enables a double-lock mechanism to maintain DNA methylation and genome stability的研究论文。该研究揭示一种维持植物DNA甲基化和基因组稳定的新机制。

  wulunshiburudongwuhaishizhiwu,qijiyinzushangbaomidingjianjidi5getanyuanzishangdoucunzaijiajihua(-ch3)dexiushi。chulezhengchangdejiyinyiwai,jiyinzuzhonghaicunzaidaliangdetiaoyuejiyin,huoyuedetiaoyuejiyinduiyushengwugetishiweixiande,zheishiyouyutamendeyidonghuipohuaijiyinzudejiegou。dnajiajihuaxiushidehexingongnengshi“shasi”zheixietiaoyuejiyin,rangtamenyizhichuyubeiyizhidezhuangtai。yiner,shengwugetishiruheweichitiaoyuejiyinshangmianzhimidednajiajihuaxiushishibiaoguanyichuanlingyuzhongdezhongyaoyanjiufangxiang。

  zhiwuzhong,duozhongdnajiajihuadiaokongtongluhezuoweichibutongjiyinzuweizhidetiaoyuejiyinshangzhimidednajiajihuazhuangtai。ciqian,yige“jingzhi”moxingbeipubianjieshou,jijiyinzuzhongjidingdetiaoyuejiyinqidnajiajihuashiyoutedingdetujingweichi,ruchicunjiaozhangdetiaoyuejiyindezhongjianbufendechhjiajihuayoucmt2weichi;erqibianyuanbufenheduanchicundetiaoyuejiyindechhjiajihuazeyournajiedaodednajiajihua(rddm)tujingweichi。

  butongyuxianqiandemoxing,zaibenyanjiuzhong,yanjiufaxianransezhizhongsuyinziddm1tubianhou,jiejin1000gecmt2weichidnajiajihuadeweidianzhuanbianweirddmtujingweichi,biaomingzaimouxieqingkuangxia,duiyujidingweidiandnajiajihuadeweichibingbushiyichengbubiande,ershikeyilinghuozhuanhuande,yinerdnajiajihuadeweichitujingzaijidingweidianshikexiugaide。keyanrenyuanjiangzheigejizhimingmingweicmt2-zhi-rddmtonglu。jinyibu,yanjiutongguoduotubiantizuduancmt2daorddmtongludezhuanhuanfaxiandaliangdetiaoyuejiyinbeijihuo,qiezaixiangyingdetubiantizhongtiaoyue,biaomingtongluzhuanhuanduiyuweichijiyinzudewendingshibixude。yanjiutichuyizhong“shuangbaoxian”shexiang:rddmtonglugongnengquefashi,ransezhizhongsuyinziddm1yilaidednajiajihuaweichitujingbaozhengtiaoyuejiyinchuyuchenmozhuangtai;dangddm1gongnengquefashi,rddmtujingbaokuoxinfaxiandecmt2-zhi-rddmtujingnenggouyizhitiaoyuejiyin。

  yanjiugongzuodedao九州体育官方网站dezizhu。

   

fenzizhiwuzhuoyuezhongxinjieshiweichidnajiajihuahejiyinzuwendingdexinjizhi

打印 责任编辑:侯茜
  • 研究发现2.9亿年前瓣齿鲨

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